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With vigilent water changes and/or low bioload/coral warfare, a skimmer is competely unnecessary. Keep tabs on your parameters (Nitrates/phosphates) and you'll know when it is no longer "good enough".
i would skip the prizm. i tried this myself. 10 Gal with prizm. prizm is a pain to get to work right. i.e. wet/dry skim control is a bit tricky and it's pretty noisy too... i say what everyone said above. stay with water change and skip prizm.
You should be fine . Without the skimmer you will have to be more diligent on your maintenance and water changes. There are a few good threads on RC about skimmerless tanks . With the proper live rock,sand and a good flow it is possible to have a real nice tank going that way . I saw on one of the tanks where the person keeps some chaeto behind the live rock . Out of site but still doing its job and adding another form of fitration.
evo - liverock is in most cases dead coral, but I'm not really understanding what your tank plans are so please forgive in advance.
Bryan - weekly 10% waterchanges can have your nano running for a really long time. And by that I mean the upgrade or boredom bug. A lite fishload and SPS maybe had as well, but YMMV depending on how SPS nutty you get. A dollar store soap basket filled with cheato can be used as an intank refugium as well. But even a refugium is not necessary.
This tank ran for 2 years before I had to tear it down to move.
Just keep up your water changes and if you can find a way to do a refugium you are set. Phyl pointed out the chemical warfare problem but without a skimmer you can still run carbon phosbane or a combo.
i have a 15 gallon without a skimmer and its been that way for the the last two months.the tank has been set up about 11months but i got tired of playing with the sea clone so i fiqured i give it a try without one. i do weekly water change and i only have 1 clown in the tank.so far so good!!